THE EFFECT OF L-FUCOSE ON RATE MAMMARY TUMOR GROWTH
James M Roseman. A. B., 1. Elizabeth Miller. Ph.D., 1
Different concentrations of L-fucose uniformly produced suppression in the growth rate and a change in the morphology of cells grown in tissue culture. The inhibition of growth of these malignant cells was found to be concentrated dependent with 100% inhibition of growth at a concentration of 50 mg fucose per millilitre of medium and 60% inhibition at a concentration of 12.5 mg fucose per millilitre medium. Using other sugars that are components of glycoproteins, it was shown that glyconutrients such as mannose and galactose could also depress the rate of growth of these tumour cells in culture. When 0.05 ml of packed tumour cells used in these experiments was resuspended in 1 ml of medium and injected into a rat, a tumour grew at the site of injection. This new tumour exhibited similar growth characteristics and showed the same histological appearance as the tumour from which the cell line was derived.
This is pretty damn exciting stuff. Yes, the study was done on rats, not humans, but what scientists in their right minds would take a chance of experimenting on human cancer patients. This is a wonderful example of a complementary modality fighting a disease with a medicine from nature. It is safe, non-toxic and non-invasive. Doesn't that make sense? None of these rats had to suffer through chemotherapy or radiation.
Since this was discovered in 1971 why didn't anybody use it? The pharmaceutical companies were interested. They attempted to make fucose into a drug. When they made fucose synthetically, it didn't work. It only works in its natural state. At that time, there was no way to patent fucose because it is a substance that occurs in nature. If you can't patent it, you can't control the profits, and if you can't control the profits, why spend the 250 million dollars in research it will take to get it approved for use by the FDA? This is why it was forgotten about and why all the tens of thousands women (and some men) who suffered from breast cancer over the last 26 years, may have done so needlessly.
Just in case one of my readers is thinking about it, there is no one to sue here. However, once doctors are made aware of this information and the fact that there is a patented product containing fucose that is available for the public (and has been since October of 1996), they would be irresponsible not to inform their patients.
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